Frozen section and permanent diagnoses of the bile duct margin in gallbladder and bile duct cancer

Intraoperative frozen section diagnosis of bile duct margin for extrahepatic cholangiocarcinoma

AIM To evaluate the usefulness of frozen section diagnosis (FSD) of bile duct margins during surgery for extrahepatic cholangiocarcinoma (CCA). METHODS We retrospectively analyzed 74 consecutive patients who underwent surgery for extrahepatic CCA from 2012 to 2017, during which FSD of bile duct margins was performed. They consisted of 40 distant and 34 perihilar CCAs (45 and 55 bile duct marg...

The protective effects of curcumin and curmumin nanomicelle against cirrhotic cardiomyopathy in bile duct-ligated rats

Objective(s): Cirrhotic cardiomyopathy refers to cardiac muscle dysfunction caused by liver cirrhosis. Seemingly, free radicals and inflammatory factors play a critical role in the pathophysiology of cardiomyopathy. Curcumin has the anti-inflammatory, antioxidant, and anticancer properties . However, the therapeutic indications of this compound are limited due to its low absorption, rapid metab...

Management of Bile Duct Problems Treatment Overview Bile Duct Obstruction

Pancreatoduodenectomy for bile duct and ampullary cancer

Pylorus-preserving pancreatoduodenectomy has become a standard operation for distal and middle bile duct cancers. Bile duct cancer typically extends longitudinally and invades vertically. It frequently metastasizes to the lymph nodes and infiltrates the perineural spaces. The presence of residual cancer in the bile duct stump and lymph node metastases are significant prognostic factors. Negativ...

Transient increase in the common bile duct diameter after laparoscopic and open cholecystectomy

Introduction: Increase in the common bile duct diameter after cholecystectomy has been reported in animal model. However, similar studies in the human resulted in controversy. Methods: Between 2008 and 2012, fifty two patients with clinical as well as radiological signs and symptoms of gallbladder disease were enrolled in this study. The patients underwent laparoscopic and open cholecystectomy ...